These 5 regenerative cell techniques used for spine and joint conditions have one thing in common – to encourage the body’s natural healing process to regenerate damaged tissues.They all rely on the fact that the necessary tissue building materials are available for the procedure to be effective. These cellular materials (if available) actually work to repair the damage and instigate pain relief. Stem Cells are only one of the techniques, here’s a run-down of how they all work –
- Adult-Derived Stem Cells – This technique extracts and reinjects a patient’s own stem cells to stimulate the body’s healing process.
- Prolotherapy – Natural substances are injected to create inflammation in the area and stimulate the body’s healing process.
- Ozone Injections – Using a highly reactive form of oxygen, the cells in the area react and stimulate the body’s healing process.
- PRP – This technique extracts and reinjects a concentrated amount of a patient’s blood platelets into the area to stimulate the body’s healing process.
- Extracellular Tissue Matrix – Using placental-derived tissue, a high concentration of tissue repair materials are placed in the area. The body’s healing process begins.
For orthopedic applications, these are the types of conditions regenerative cell therapies are used for:
- degeneration or arthritis in neck or back
- herniated (bulged or slipped) disc in neck or back
- knee, shoulder or hip osteoarthritis
- chronic pain in the spine or joints
- pain or tingling from the neck down the arms
- sciatica or radiating pain from the back into the hip or down the leg
Now that we have a basic understanding of what they are and how they work, let’s focus on just two of them – adult-derived stem cells and the placental-derived tissue matrix.
What are the differences between adult-derived stem cells and an extracellular tissue matrix (placental-derived)?
One difference is that adult-derived stem cells need to match the tissues of the donor which is why your own stem cells (autologous) are typically used. An extracellular tissue matrix (placental- derived) does not require genetic match as it is considered immune-privileged. Remember what the placenta did during the development of the baby? Let’s think of it as neutral ground when it comes to genetic side-taking. It provided a safe barrier between separate blood supplies as well as a barrier between two immune systems.
How are these treatments FDA regulated?
When a clinic uses adult-derived stem cells and does anything to add to this tissue in its own lab before re-injecting it into the damaged areas, this is looked upon as a manipulation to the tissue that should be regulated by the FDA. This is why some clinics are under scrutiny for their techniques. A donated tissue such as the placental-derived extracellular matrix must be acquired by following strict FDA guidelines and regulations before being provided to a clinic for use in a procedure. Just to clarify, we are talking about a highly concentrated placental-derived tissue matrix, not the amniotic fluid that surrounds a baby during development.
Here’s a side-by-side comparison between these two common regenerative options.
Adult-Derived Stem Cells
Extracellular Tissue Matrix (Placental-Derived)
|Cells are aged, affected by health of patient, environment and how they are acquired.||A matrix of cellular building materials – naive, unaged and viable. All components needed to build and renew healthy connective tissue are present including growth factors, collagens, proteins and bio-materials.|
|A patient procedure is required to obtain the cells. Then, a technique is used to isolate or spin out the cells for reinjection. There is potential damage to the cells during this process and possibility of staff error.||Donated tissue is stringently screened and prepared using a patented, FDA approved method. Arrives preserved in a vial until it is needed for a procedure.|
|Some clinics that are providing stem cell procedures are being reviewed by the FDA for their preparation techniques.||FDA regulations and guidelines are in place for donated tissue. In-house processing or manipulation of the product is not necessary.|
|Stem cells can be beneficial, but are most effective if building bio-materials are present in the environment. As the environment is an area in need of repair, that is in indicator that these building materials are needed.||The extracellular tissue matrix is the key to an enhanced regenerative environment. The bio-materials found in the tissue matrix are the necessary parts needed to start the repairing, rebuilding process.|
To summarize, we choose the placental-derived tissue matrix over adult-derived stem cells for these reasons:
- Viable, un-aged cellular building materials.
- Less invasive procedure for patients.
- Efficient, uncompromised preparation of cellular tissue.
- FDA Regulated donated tissue.
- Tissue Matrix includes collagen, proteins and biomaterials necessary for the body’s natural repair process.
Before a clinic advises you that, “this will work for you,” there should be a comprehensive review of your condition and current x-rays or MRI’s by a musculoskeletal expert. We offer a FREE CONSULT with a trained specialist to assess your specific condition and will give you our best recommendations whether or not we offer them at our clinic. Are you in pain and need to find out what your options are? Schedule a consult to find out if EMTX Renew™ Treatment is right for you? What can it hurt to find out? Call us at (801)756-7800.
Phone consults are available for our out-of-town inquiries.